B Cell Depletion Inhibits Fibrosis via Suppression of Profibrotic Macrophage Differentiation in a Mouse Model of Systemic Sclerosis - Concepedia

Concepedia

Publication | Closed Access

B Cell Depletion Inhibits Fibrosis via Suppression of Profibrotic Macrophage Differentiation in a Mouse Model of Systemic Sclerosis

43

Citations

32

References

2021

Year

Hiroko Numajiri, Ai Kuzumi, Takemichi Fukasawa, Satoshi Ebata, Asako Yoshizaki‐Ogawa, Yoshihide Asano, Yutaka Kazoe, Kazuma Mawatari, Takehiko Kitamori, Ayumi Yoshizaki,

Arthritis & Rheumatology

Abstract

These findings suggest that B cell depletion inhibits tissue fibrosis via suppression of profibrotic macrophage differentiation in mice with BLM-SSc, providing a new rationale for B cell depletion therapy in SSc.

References

	Year	Citations

Page 1