An excellent electrochemical aptasensor for amyloid-β oligomers based on a triple-helix aptamer switch via target-triggered signal transduction DNA displacement events

In Vitro Characterization of Conditions for Amyloid-β Peptide Oligomerization and Fibrillogenesis

W. Blaine Stine, Karie N. Dahlgren, Grant A. Krafft et al. · Journal of Biological Chemistry · 2003 · 1K citations · Full text

Life Sciences, Biochemistry, Neuroscience +17

Aptamer-Modified Gold Nanoparticles for Colorimetric Determination of Platelet-Derived Growth Factors and Their Receptors

Chih‐Ching Huang, Yu‐Fen Huang, Zehui Cao et al. · Analytical Chemistry · 2005 · 542 citations

Engineering, Bioengineering, Biomedical Engineering +17

A Reagentless Signal-On Architecture for Electronic, Aptamer-Based Sensors via Target-Induced Strand Displacement

Yi Xiao, Brian Piorek, Kevin W. Plaxco et al. · Journal of the American Chemical Society · 2005 · 521 citations

Engineering, Bioengineering, Molecular Biology +17

Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrils

Jan Bieschke, Martin Herbst, Thomas Wiglenda et al. · Nature Chemical Biology · 2011 · 442 citations

Life Sciences, Biochemistry, Molecular Biology +15

Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer’s disease

Xueli Zhang, Yanli Tian, Can Zhang et al. · Proceedings of the National Academy of Sciences · 2015 · 230 citations · Full text

Medicine, Molecular Biology, Pharmacology +16