Concepedia

Caveolin‐1‐driven membrane remodelling regulates hnRNPK‐mediated exosomal microRNA sorting in cancer

Harley Robinson, Jayde E. Ruelcke, Amanda J. Lewis, Charles S. Bond, Archa H. Fox, Vandhana Bharti, Shivangi Wani, Nicole Cloonan, Andrew Lai, David A. Margolin,

Clinical and Translational Medicine · 2021 · 53 citations · 49 references

DOIFull text

Open access

Abstract

Taken together, these results support a novel pan-cancer mechanism for CAV1-driven exosomal release of hnRNPK and associated miRNA in metastasis, which is modulated by the membrane lipid environment.

References

49

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Huili Guo, Nicholas T. Ingolia, Jonathan S. Weissman et al. · Nature · 2010 · 3.9K citations · Full text

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