Suppressing Kv1.3 Ion Channel Activity with a Novel Small Molecule Inhibitor Ameliorates Inflammation in a Humanised Mouse Model of Ulcerative Colitis - Concepedia

Concepedia

Publication | Open Access

Suppressing Kv1.3 Ion Channel Activity with a Novel Small Molecule Inhibitor Ameliorates Inflammation in a Humanised Mouse Model of Ulcerative Colitis

DOI Full Paper Access

16

Citations

32

References

2021

Year

Anna‐Lena Unterweger, Morten Ø. Jensen, Fabrizio Giordanetto, Vishwanath Jogini, Alena Rüschher, Marietta Seuß, Paula Winkelmann, Leandra Koletzko, David E. Shaw, Matthias Siebeck,

Journal of Crohn s and Colitis

Abstract

Inhibition of Kv1.3 [by DES1, for instance] appears to be a potential therapeutic intervention strategy for UC patients.

References

	Year	Citations

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