High turnover of types <scp>III</scp> and <scp>VI</scp> collagen in progressive idiopathic pulmonary fibrosis

Abstract

Blood biomarkers of types III and VI collagen turnover, assessed at the time of diagnosis, are associated with several indices of disease severity, short-term progression and long-term mortality. These biomarkers can help to identify patients with a high ECM remodelling phenotype at high risk of disease progression and death.