Publication | Closed Access
Optimization of conditions for supercritical fluid extraction of flavonoids from hops (Humulus lupulus L.)
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2005
Year
Food ChemistryExtraction OfflavonoidsChemical EngineeringGood Sources OfflavonoidsWaste HopsEngineeringSupercritical Fluid ChromatographyPolyphenolicsEnvironmental EngineeringMedicineSolvent ExtractionSupercritical FlowAnalytical ChemistrySupercritical Fluid ExtractionPhytochemicalPhytochemistryPharmacologyChromatography
Waste hops are good sources offlavonoids. Extraction offlavonoids from waste hops (SC-CO2 extracted hops) using supercritical fluids technology was investigated. Various temperatures, pressures and concentrations of ethanol (modifier) and the ratio (w/w) of solvent to material were tested in this study. The results of single factor and orthogonal experiments showed that at 50℃, 25 MPa, the ratio of solvent to material (50%), ethanol concentration (80%) resulted in maximum extraction yield flavonoids (7.8 mg/g). HPLC-MS analysis of the extracts indicated that flavonoids obtained were xanthohumol, the principal prenylflavonoid in hops.