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Ghrelin and cell differentiation
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2008
Year
Mesenchymal Stem CellsCell PhysiologyDevelopmental BiologySignal TransductionCell DivisionCell SpecializationEndocrine MechanismGrowth HormonePhysiologyMorphogenesisCell DifferentiationGlucocorticoidEndocrinologyMedicineCell BiologyCellular PhysiologyGastric HormoneGastrointestinal Peptide Hormone
Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, is a gastric hormone that has been found to have a wide variety of biological functions. This review summarizes our current understanding of the effects of ghrelin on cell differentiation and tissue development, with an emphasis on the lineage determination of mesenchymal stem cells.