A Turn-ON fluorometric biosensor based on ssDNA immobilized with a metal phenolic nanomaterial for the sequential detection of Pb(<scp>ii</scp>) and epirubicin cancer drug

Abstract

In this paper, we propose a fluorescent biosensor for the sequential detection of Pb²⁺ ions and the cancer drug epirubicin (Epn) using the interactions between label-free guanine-rich ssDNA (LFGr-ssDNA), acridine orange (AO), and a metal–phenolic nanomaterial.