Concepedia

Mebhydrolin ameliorates glucose homeostasis in type 2 diabetic mice by functioning as a selective FXR antagonist

Tong Zhao, Jie Wang, Anxu He, Shan Wang, Yidi Chen, Jian Lu, Jianlu Lv, Shiliang Li, Jiaying Wang, Minyi Qian,

Metabolism · 2021 · 37 citations · 35 references

DOI

Concepts

References

35

[20] VERIFY3D: Assessment of protein models with three-dimensional profiles

David Eisenberg, Roland Lüthy, James U. Bowie · Methods in enzymology on CD-ROM/Methods in enzymology · 1997 · 2.2K citations

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An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

Huanting Liu, James H. Naismith · BMC Biotechnology · 2008 · 1.3K citations · Full text

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Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

Yanqiao Zhang, Florence Ying Lee, Gabriel Barrera et al. · Proceedings of the National Academy of Sciences · 2006 · 937 citations · Full text

, , +17

Farnesoid X receptor is essential for normal glucose homeostasis

Ke Ma · Journal of Clinical Investigation · 2006 · 863 citations · Full text

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Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

Changtao Jiang, Cen Xie, Ying Lv et al. · Nature Communications · 2015 · 537 citations · Full text

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