Concepedia

Identification and characterization of degradation products of Remdesivir using liquid chromatography/mass spectrometry

S. Babu Dadinaboyina, Naga Veera Yerra, Bala Manikantha Adimoolam, Sivaramakrishna Parsa, Bathini Nagendra Babu, Jagadeshwar Reddy Thota

New Journal of Chemistry · 2021 · 25 citations · 15 references

DOI

Concepts

Abstract

A total of nine degradation products were identified under different stress conditions by using LC-MS for RDV.

References

15

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

Ali M. Zaki, Sander van Boheemen, Theo M. Bestebroer et al. · New England Journal of Medicine · 2012 · 6K citations · Full text

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Identification of a Novel Coronavirus in Patients with Severe Acute Respiratory Syndrome

Christian Drosten, Stephan Günther, Wolfgang Preiser et al. · New England Journal of Medicine · 2003 · 4.8K citations · Full text

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A Novel Coronavirus Associated with Severe Acute Respiratory Syndrome

Dean D. Erdman, Goldsmith Cs, Zaki et al. · New England Journal of Medicine · 2003 · 4.5K citations

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Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

Maria L. Agostini, Erica L. Andres, Amy Sims et al. · mBio · 2018 · 1.5K citations · Full text

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Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection

Emmie de Wit, Friederike Feldmann, Jacqueline Cronin et al. · Proceedings of the National Academy of Sciences · 2020 · 946 citations · Full text

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