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Switching to riociguat versus maintenance therapy with phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension (REPLACE): a multicentre, open-label, randomised controlled trial

HypertensionPulmonary Arterial HypertensionPhosphodiesterase-5 InhibitorsCardiovascular DiseaseMedicineAntihypertensive TherapyCardiovascular PharmacologyVersus Maintenance TherapyPharmacotherapyPharmacologic InterventionPublic HealthPharmacologyPulmonary Vascular DiseaseAnesthesiology