Acta Ophthalmologica · 2021 · 11 citations · 33 references
MedicineOphthalmologySurgeryClinical Vision ScienceOphthalmic SurgeryRefractive SurgeryCongenital GlaucomaGlaucomaGlaucoma SurgeryIntraocular Pressure MeasurementUveal SurgeryCongenital Glaucoma SurgeryGlaucoma After Cataract SurgeryIntraocular Pressure ElevationIntraocular Pressure ManagementIntraocular Pressure ReductionLong-term Efficacy EvaluationPostoperative Glaucoma Follow-upSurgical Outcomes In Glaucoma
PURPOSE: To evaluate the long-term efficacy and safety of circumferential trabeculotomy (CT) in the treatment of primary congenital glaucoma (PCG). METHODS: Retrospective, single-institutional case series of CT performed for PCG in years 1997-2016. The surgery could be completed in 42 out of 65 eyes (65%) intended for CT, and 39 of them were included in the study. A follow-up examination was performed in 2017. Success was defined as intraocular pressure ≤ 16 mmHg without (complete) or with (qualified) glaucoma medication. RESULTS: Complete success was obtained in 33/39 eyes (85%), qualified success in 34/39 eyes (87%). Of the 39 eyes with CT, 4 eyes (10%) needed additional surgery. Median follow-up time was 120 months (range, 19-245 months). Median pre- and postoperative IOP were 26.0 mmHg (range, 10-41 mmHg) and 11.0 mmHg (range, 8-19 mmHg), respectively (p < 0.001). Cup-disc ratio was ≥0.5 in 82% at baseline, at follow-up in 9%. The median distance corrected visual acuity at follow-up was logMAR 0.06 (range, -0.2 to 1.1). Median number of glaucoma medication at follow-up was 0 (range, 0-2), at baseline 1.0 (range, 0-2). No serious complications were noted. CONCLUSION: Circumferential trabeculotomy is an efficacious, safe and medication saving surgical treatment for PCG in the long term. After a median follow-up of 10 years (120 months), the morphological status of the optic nerve was either normalized or stabilized, and the visual acuity overall well preserved.
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R: A Language and Environment for Statistical Computing
R Core Team · 2000 · 353K citations · Full text
Natural Sciences, Computer Science, Statistical Computing +10
The British Infantile and Childhood Glaucoma (BIG) Eye Study
Maria Papadopoulos, Noriko Cable, Jugnoo S. Rahi et al. · Investigative Ophthalmology & Visual Science · 2007 · 313 citations
Medicine, Ophthalmology, Pediatrics +17
Results, with Trabeculotomy and Study of Reversible Cupping
Harry A. Quigley · Ophthalmology · 1982 · 233 citations
Medicine, Ophthalmology, Surgery +2