Journal of Oral and Maxillofacial Pathology · 2020 · 10 citations · 8 references
MedicineInfectious DiseasesPathologyMedical MicrobiologyMycologyRhinologyFungal DiagnosticsFungal InfectionsFungal PathogenesisFungal PathologyOral Mucosal DiseasesOral Mucosal LesionsCytological ExaminationFungal Infections In Immunocompromised HostsHistopathological EvaluationHost-fungus InteractionsMucormycosis DiagnosisNasal MycosisOverall MortalityPathology Misdiagnosis
Mucormycosis is an emerging fungal infection which has exceptionally high mortality rates in immunocompromised patients and remains a life-threatening infection in uncontrolled diabetics. The reported cases in literature may be less in number due to its frequent misdiagnosis. Imaging techniques in the early stages are usually nondiagnostic and cytological smears are not very reliable, thus, the gold standard for definitive diagnosis remains with the histopathological examination. A thorough understanding of the pathogenesis and host fungus interaction aids in the histopathological evaluation and clinical management. Despite of surgical and medical management, the overall mortality rate remains high in persistently immunocompromised individuals. We present a case report of a 58-year-old female patient with rhinomaxillary mucormycosis with a history of uncontrolled diabetes.
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