Journal of Clinical Microbiology · 2021 · 26 citations · 42 references
Veterinary MedicineImmunologyInfectious DiseasesImmunizationImmunology Of Infectious DiseasesVaccine ImmunologyAntigen Detection AssaysDiagnostic ImmunologyPediatric ImmunizationSerological DiagnosticsVaccinationVaccine-preventable DiseasesMultiplex Diagnostic AssaysMultiplex DiagnosticsMultiplex SerodiagnosticsMultiplex Serological AssaysMultiplex SerologyPopulation Immunity AssessmentSerological DetectionSerological Testing For Immunity
= 0.919). ROC analysis of the rubella MBA using ELISA as the comparator yielded a cutoff of 9.36 IU/ml, similar to the accepted cutoff of 10 IU/ml for seroprotection, with a sensitivity of 99% and a specificity of 100%. These results support use of the MBA for multiantigen serosurveys assessing measles and rubella population immunity.
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