Concepedia

PI3K/Akt/GSK-3β signal pathway is involved in P2X7 receptor-induced proliferation and EMT of colorectal cancer cells

Wenjun Zhang, Chen Luo, Chao Huang, Fan-qin Pu

European Journal of Pharmacology · 2021 · 60 citations · 27 references

DOI

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References

27

Molecular mechanism of ATP binding and ion channel activation in P2X receptors

Motoyuki Hattori, Eric Gouaux · Nature · 2012 · 560 citations

, , +17

P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death

Davide Ferrari, Manuel Bauer, Peter Vandenabeele et al. · FEBS Letters · 1999 · 273 citations · Full text

, , +13

P2X7 receptor activation enhances SK3 channels- and cystein cathepsin-dependent cancer cells invasiveness

Bilel Jelassi, Aurélie Chantôme, Francisca Alcaraz‐Pérez et al. · Oncogene · 2011 · 206 citations

, , +9

ATP in the tumour microenvironment drives expression of nfP2X7, a key mediator of cancer cell survival

S.M. Gilbert, CJ Oliphant, Sakinah Hassan et al. · Oncogene · 2018 · 203 citations · Full text

, , +9

Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-κB

Marco Tafani, Luana Schito, Laura Pellegrini et al. · Carcinogenesis · 2011 · 168 citations

, , +17