Chemical Communications · 2021 · 62 citations · 21 references
Life SciencesBiochemistryBiophysicsBiomedical OpticsMitochondrial BiologyMolecular ImagingBlood ViscosityMitochondrial PhysiologyFluorescent BiosensingFluorescent Probe DesignFluorescent SensorsHypoxic Microenvironment
A novel mitochondria-targeting molecular rotator FD was designed to visualize changes in viscosity under hypoxic conditions in vitro and in vivo. Importantly, FD can be used to detect changes in the blood viscosity of liver cancer and liver cirrhosis patients, and also rehabilitation of liver disease.
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