Aging · 2021 · 111 citations · 57 references
Life SciencesGeneticsMolecular BiologyEpigeneticsEpigenomicsGenomicsDna Methylation ProfilingDna SequencingEpigenetic Biomarker AnalysisEpigenetic Biomarker DiscoveryEpigenetic BiomarkersEpigenetics Of AgingAge-related Methylation MarkersBiological Age BiomarkersBisulfite SequencingDna Methylation PatternsEpigenetic Age EstimationEpigenetic Aging MarkersMean Absolute ErrorSite-specific Dna Methylation Markers
and predicts age with MAE of 3.4 years. The VISAGE enhanced tool for age estimation in somatic tissues enables reliable collection of DNA methylation data from small amounts of DNA using a sensitive multiplex MPS assay that provides accurate estimation of age in blood, buccal swabs, and bones using the statistical model tailored to each tissue.
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The Sequence Alignment/Map format and SAMtools
Heng Li, Alec Wysoker, Tim Fennell et al. · Bioinformatics · 2009 · 67.5K citations · Full text
DNA methylation age of human tissues and cell types
Steve Horvath · Genome biology · 2013 · 7.3K citations · Full text
Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates
Gregory Hannum, Justin Guinney, Ling Zhao et al. · Molecular Cell · 2012 · 4.5K citations · Full text
An epigenetic biomarker of aging for lifespan and healthspan
Morgan E. Levine, Ake T. Lu, Austin Quach et al. · Aging · 2018 · 3.6K citations · Full text