Protective effects of berberine in a rat model of polycystic ovary syndrome mediated via the <scp>PI3K</scp>/<scp>AKT</scp> pathway

Abstract

The beneficial effects of Ber on PCOS included alterations of the serum hormone levels, recovery of morphological lesions in the ovary, improvement of insulin resistance, and cell viability and inhibition of apoptosis, which were all mediated through the PI3K/AKT pathway.