Inhibition of CPT1a as a prognostic marker can synergistically enhance the antileukemic activity of ABT199 - Concepedia

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Inhibition of CPT1a as a prognostic marker can synergistically enhance the antileukemic activity of ABT199

DOI Full Paper Access

32

Citations

16

References

2021

Year

Shihui Mao, Qing Ling, Jiajia Pan, Fenglin Li, Shujuan Huang, Wenle Ye, Wenwen Wei, Xiangjie Lin, Qian Yu, Yungui Wang,

Journal of Translational Medicine

Abstract

Our study indicates that overexpression of CPT1a predicts poor clinical outcome in AML. CPT1a-selective inhibitor ST1326 combined with Bcl-2 inhibitor ABT199 showed strong synergistic inhibitory effects on AML.

References

	Year	Citations

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