Dihydroartemisinin induces pyroptosis by promoting the AIM2/caspase-3/DFNA5 axis in breast cancer cells

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

Yupeng Wang, Wenqing Gao, Xuyan Shi et al. · Nature · 2017 · 3.2K citations

Life Sciences, Cell Biology, Oncology +13

Breast Cancer Molecular Subtypes Respond Differently to Preoperative Chemotherapy

Roman Rouzier, Charles M. Perou, W. Fraser Symmans et al. · Clinical Cancer Research · 2005 · 1.9K citations · Full text

Medicine, Cancer Biology, Oncology +17

Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death

Corey Rogers, Teresa Fernandes‐Alnemri, Lindsey Mayes et al. · Nature Communications · 2017 · 1.5K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation

Corey Rogers, Dan A. Erkes, Alexandria Nardone et al. · Nature Communications · 2019 · 831 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

The lncRNA Neat1 promotes activation of inflammasomes in macrophages

Pengfei Zhang, Limian Cao, Rongbin Zhou et al. · Nature Communications · 2019 · 513 citations · Full text

Life Sciences, Immunology, Molecular Biology +17