Concepedia

Semimechanistic Pharmacokinetic/Pharmacodynamic Modeling of Fosfomycin and Sulbactam Combination against Carbapenem-Resistant Acinetobacter baumannii

Sazlyna Mohd Sazlly Lim, Aaron J. Heffernan, Jason A. Roberts, Fekade B. Sime

Antimicrobial Agents and Chemotherapy · 2021 · 12 citations · 22 references

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Abstract

Due to limited treatment options for carbapenem-resistant Acinetobacter baumannii (CR-AB) infections, antibiotic combinations are now considered potential treatments for CR-AB. This study aimed to explore the utility of fosfomycin-sulbactam combination (FOS/SUL) therapy against CR-AB isolates.

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