Concepedia

Emetine suppresses SARS-CoV-2 replication by inhibiting interaction of viral mRNA with eIF4E

Ram Kumar, Mohammed Afsar, Nitin Khandelwal, Yogesh Chander, Thachamvally Riyesh, Ramesh Kumar Dedar, Baldev R. Gulati, Yash Pal, Sanjay Barua, Bhupendra Nath Tripathi,

Antiviral Research · 2021 · 63 citations · 29 references

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29

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

David E. Gordon, Gwendolyn Μ. Jang, Mehdi Bouhaddou et al. · Nature · 2020 · 4.9K citations · Full text

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Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro

Ka-Tim Choy, Alvina Y. L. Wong, Prathanporn Kaewpreedee et al. · Antiviral Research · 2020 · 972 citations · Full text

, , +11

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine

Wilson Wong, Xiao‐chen Bai, Alan Brown et al. · eLife · 2014 · 378 citations · Full text

, , +17

Inhibitors of Protein Biosynthesis

Arthur P. Grollman · Journal of Biological Chemistry · 1968 · 233 citations · Full text

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STRUCTURAL BASIS FOR INHIBITION OF PROTEIN SYNTHESIS BY EMETINE AND CYCLOHEXIMIDE BASED ON AN ANALOGY BETWEEN IPECAC ALKALOIDS AND GLUTARIMIDE ANTIBIOTICS

Arthur P. Grollman · Proceedings of the National Academy of Sciences · 1966 · 225 citations · Full text

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