Concepedia

KnowVolution of prodigiosin ligase PigC towards condensation of short-chain prodiginines

Stefanie Brands, Hannah U. C. Brass, Andreas Klein, Jarno G. Sikkens, Mehdi D. Davari, Jörg Pietruszka, Anna Joëlle Ruff, Ulrich Schwaneberg

Catalysis Science & Technology · 2021 · 14 citations · 57 references

DOI

Concepts

Abstract

One round of KnowVolution enhanced the catalytic activity of prodigiosin ligase PigC with short-chain monopyrroles, opening access to anticancer prodiginines.

References

57

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Ambrish Roy, Alper Küçükural, Yang Zhang · Nature Protocols · 2010 · 6.3K citations · Full text

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ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins

Markus Wiederstein, Manfred J. Sippl · Nucleic Acids Research · 2007 · 6K citations · Full text

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MolProbity: More and better reference data for improved all‐atom structure validation

Christopher J. Williams, Jeffrey J. Headd, Nigel W. Moriarty et al. · Protein Science · 2017 · 5K citations · Full text

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Verification of protein structures: Patterns of nonbonded atomic interactions

Christos Colovos, Todd O. Yeates · Protein Science · 1993 · 4.5K citations · Full text

, , +7