Concepedia

Lactate-induced M2 polarization of tumor-associated macrophages promotes the invasion of pituitary adenoma by secreting CCL17

Anke Zhang, Yuanzhi Xu, Houshi Xu, Jie Ren, Tong Meng, Yunjia Ni, Qingwei Zhu, Wen‐Bo Zhang, Yuanbo Pan, Jiali Jin,

Theranostics · 2021 · 211 citations · 29 references

DOIFull text

Open access

Concepts

Abstract

M2 polarization. CCL17 levels in the TME are related to the PA invasiveness and clinical prognosis, and the CCL17/CCR4/mTOCR1 axis may serve as potential therapeutic targets for Pas.

References

29

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, , +10

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Macrophage IL-10 Blocks CD8+ T Cell-Dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells

Brian Ruffell, Debbie Chang-Strachan, Vivien W. Chan et al. · Cancer Cell · 2014 · 988 citations · Full text

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Tumor-Associated Neutrophils Recruit Macrophages and T-Regulatory Cells to Promote Progression of Hepatocellular Carcinoma and Resistance to Sorafenib

Shao‐Lai Zhou, Zheng‐Jun Zhou, Zhiqiang Hu et al. · Gastroenterology · 2016 · 895 citations · Full text

, , +17