Vitamin D Inhibits Adipokine Production and Inflammatory Signaling Through the Vitamin D Receptor in Human Adipocytes - Concepedia

Concepedia

Publication | Closed Access

Vitamin D Inhibits Adipokine Production and Inflammatory Signaling Through the Vitamin D Receptor in Human Adipocytes

35

Citations

38

References

2021

Year

Hataikarn Nimitphong, Weimin Guo, Michael F. Holick, Susan K. Fried, Mi‐Jeong Lee

Abstract

Vitamin D acts through VDR to inhibit inflammatory pathways and adipokine expression in human adipocytes. Increasing vitamin D status may ameliorate obesity-associated metabolic complications by decreasing adipose tissue inflammation.

References

	Year	Citations
Decreased bioavailability of vitamin D in obesity Jacobo Wortsman, Lois Y. Matsuoka, Tai C. Chen, American Journal of Clinical Nutrition ObesityMetabolic SyndromeNutritionBody CompositionPhysiology	2000	3.1K
Omental and Subcutaneous Adipose Tissues of Obese Subjects Release Interleukin-6: Depot Difference and Regulation by Glucocorticoid Susan K. Fried The Journal of Clinical Endocrinology & Metabolism Metabolic DisorderImmunologyGlucocorticoidObesityInflammation	1998	1.1K
Vitamin D Inhibits Monocyte/Macrophage Proinflammatory Cytokine Production by Targeting MAPK Phosphatase-1 Yong Zhang, Donald Y.M. Leung, Brittany Richers, The Journal of Immunology ImmunologyImmune RegulationInnate ImmunityOxidative StressInflammation	2012	848
Volumetric Dilution, Rather Than Sequestration Best Explains the Low Vitamin D Status of Obesity Andjela Drincic, Laura Armas, Eileen E. van Diest, Obesity NutritionMetabolic DisorderOsteoporosisObesityMetabolic Syndrome	2012	609
Vitamin D Receptor Inhibits Nuclear Factor κB Activation by Interacting with IκB Kinase β Protein Yunzi Chen, Jing Zhang, Xin Ge, Journal of Biological Chemistry InflammationSignal TransductionMolecular PhysiologyReceptor Tyrosine KinaseImmunology	2013	351
1α,25‐Dihydroxyvitamin D <sub>3</sub> modulates human adipocyte metabolism via nongenomic action Hang Shi, Anthony W. Norman, William H. Okamura, The FASEB Journal	2001	251
Paricalcitol Inhibits Renal Inflammation by Promoting Vitamin D Receptor–Mediated Sequestration of NF-κB Signaling Xiaoyue Tan, Xiao‐Yan Wen, Youhua Liu Journal of the American Society of Nephrology	2008	250
Expression of vitamin D-metabolizing enzymes in human adipose tissue—the effect of obesity and diet-induced weight loss Louise Wamberg, Terkel Christiansen, Søren K. Paulsen, International Journal of Obesity ObesityNutritionMetabolic SyndromeMetabolic DisorderBiochemistry	2012	249
Increased NF-κB activity in fibroblasts lacking the vitamin D receptor Jun Sun, Juan Kong, Yingli Duan, American Journal of Physiology-Endocrinology and Metabolism ImmunologyImmune RegulationPathologyCell DeathIkappabalpha Degradation	2006	228
Vitamin D-Binding Protein Directs Monocyte Responses to 25-Hydroxy- and 1,25-Dihydroxyvitamin D Rene F. Chun, Anna Lis Lauridsen, Lizabeth Suon, The Journal of Clinical Endocrinology & Metabolism	2010	226

Page 1