Cisatracurium regulates the CXCR4/let-7a-5p axis to inhibit colorectal cancer progression by suppressing TGF-β/SMAD2/3 signalling

Cancer statistics, 2019

Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2019 · 21K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Global patterns and trends in colorectal cancer incidence and mortality

Melina Arnold, Mónica S. Sierra, Mathieu Laversanne et al. · Gut · 2016 · 5.3K citations · Full text

Medicine, Oncology, Population Health Sciences +17

Prognostic and Predictive Relevance of Primary Tumor Location in Patients With <i>RAS </i>Wild-Type Metastatic Colorectal Cancer

Sabine Tejpar, Sebastian Stintzing, Fortunato Ciardiello et al. · JAMA Oncology · 2016 · 722 citations · Full text

Medicine, Cancer Biology, Oncology +17

Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer

Ivy X. Chen, Vikash P. Chauhan, Jessica M. Posada et al. · Proceedings of the National Academy of Sciences · 2019 · 398 citations · Full text

Medicine, Immunology, Oncology +17

CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia

Ye Chen, Rodrigo Jácamo, Marina Konopleva et al. · Journal of Clinical Investigation · 2013 · 209 citations · Full text

Life Sciences, Molecular Biology, Oncology +16