The mitochondrial-derived peptide MOTS-c promotes homeostasis in aged human placenta-derived mesenchymal stem cells in vitro

Evidence that brain‐derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice

Jaewon Lee, Wenzhen Duan, Mark P. Mattson · Journal of Neurochemistry · 2002 · 967 citations

Medicine, Neurobiology, Neuroscience +14

Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR‐γ2 transcription factor and TGF‐β/BMP signaling pathways

Elena J. Moerman, Kui Teng, David A. Lipschitz et al. · Aging Cell · 2004 · 852 citations · Full text

Medicine, Cell Biology, Developmental Biology +17

The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance

Changhan Lee, Jennifer Zeng, Brian G. Drew et al. · Cell Metabolism · 2015 · 725 citations · Full text

Life Sciences, Cell Biology, Physiology +13

mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells

Chong Chen, Yu Liu, Pan Zheng · Science Signaling · 2009 · 686 citations · Full text

Life Sciences, Cell Biology, Pharmacotherapy +17

Changes in phenotype and differentiation potential of human mesenchymal stem cells aging in vitro

Yueh‐Hsun Yang, Courtney R. Ogando, Carmine Wang See et al. · Stem Cell Research & Therapy · 2018 · 648 citations · Full text

Life Sciences, Cell Biology, Aging +16