Concepedia

Endothelial Regulation by Exogenous Annexin A1 in Inflammatory Response and BBB Integrity Following Traumatic Brain Injury

Han Liu, Junchi He, Yue Wu, Yang Du, Yinghua Jiang, Chengzhi Chen, Zhanyang Yu, Jianjun Zhong, Zhigang Wang, Chongjie Cheng,

Frontiers in Neuroscience · 2021 · 35 citations · 27 references

DOIFull text

Open access

Abstract

Our findings suggest that the endothelial remodeling by exogenous rANXA1 corrects BBB disruption and inflammatory response through RhoA inhibition, hence improving functional outcomes in CCI mice.

References

27

Very Early Administration of Progesterone for Acute Traumatic Brain Injury

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Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery

Daniel Tornero, Somsak Wattananit, Marita Grønning Madsen et al. · Brain · 2013 · 238 citations · Full text

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Intracerebral administration of interleukin-1β and induction of inflammation, apoptosis, and vasogenic edema

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Identification of an essential endogenous regulator of blood–brain barrier integrity, and its pathological and therapeutic implications

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