Concepedia

Anti-inflammatory activity of novel thiosemicarbazone compounds indole-based as COX inhibitors

Íris Trindade Tenório Jacob, Fabiana Gomes, Mirelly Dianne Santos de Miranda, Sinara Mônica Vitalino de Almeida, Iranildo José da Cruz Filho, Christina Alves Peixoto, Teresinha G. da Silva, Diogo Rodrigo Magalhães Moreira, Cristiane Moutinho Lagos de Melo, Jamerson Ferreira de Oliveira,

Pharmacological Reports · 2021 · 53 citations · 48 references

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48

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

Antoine Daina, Olivier Michielin, Vincent Zoete · Scientific Reports · 2017 · 17.1K citations · Full text

, , +16

Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 8.1K citations

, , +15

Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs

C. A. Winter, Edwin A. Risley, George W. Nuss · Experimental Biology and Medicine · 1962 · 5.7K citations

, , +7

pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures

Douglas E. V. Pires, Tom L. Blundell, David B. Ascher · Journal of Medicinal Chemistry · 2015 · 5.4K citations · Full text

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Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

Aihao Ding, Carl Nathan, Dennis J. Stuehr · The Journal of Immunology · 1988 · 2.8K citations · Full text

, , +17