Concepedia

Faster palladium-catalyzed arylation of simple arenes in the presence of a methylketone: beneficial effect of an <i>a priori</i> interfering solvent in C–H activation

Vanesa Salamanca, Ana C. Albéniz

Organic Chemistry Frontiers · 2021 · 20 citations · 58 references

DOIFull text

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Concepts

Abstract

A methyl ketone accelerates the Pd-catalyzed C–H activation of simple arenes. A noninnocent solvent, it reacts in a reversible way without affecting the outcome of the reaction.

References

58

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

Keary M. Engle, Tian‐Sheng Mei, Masayuki Wasa et al. · Accounts of Chemical Research · 2011 · 2.7K citations

, , +16

COPASI—a COmplex PAthway SImulator

Stefan Hoops, Sven Sahle, Ralph Gauges et al. · Bioinformatics · 2006 · 2.7K citations · Full text

, , +14

On the Interpretation of Deuterium Kinetic Isotope Effects in CH Bond Functionalizations by Transition‐Metal Complexes

Eric M. Simmons, John F. Hartwig · Angewandte Chemie International Edition · 2012 · 2.1K citations

, , +14

CHEM21 selection guide of classical- and less classical-solvents

Denis Prat, A.S. Wells, John Hayler et al. · Green Chemistry · 2015 · 2.1K citations · Full text

, , +10

Beyond Directing Groups: Transition‐Metal‐Catalyzed CH Activation of Simple Arenes

Nadine Kuhl, Matthew N. Hopkinson, Joanna Wencel‐Delord et al. · Angewandte Chemie International Edition · 2012 · 1.6K citations

, , +14