Ocrelizumab treatment reduced levels of neurofilament light chain and numbers of B cells in the cerebrospinal fluid of patients with relapsing multiple sclerosis in the OBOE study (S56.008)

Anne H. Cross, Jeffrey L. Bennett, H.-Christian von Büdingen, Robert Carruthers, Keith R. Edwards, Robert J. Fallis, Damian Fiore, Jeffrey M. Gelfand, Paul S. Giacomini, Benjamin Greenberg,

Neurology · 2019 · 16 citations · 0 references

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Abstract

To provide interim analysis (IA) results from the relapsing multiple sclerosis (RMS) cohort of OBOE (Ocrelizumab Biomarker Outcome Evaluation; NCT02688985), a cerebrospinal fluid (CSF) and blood biomarker study.