Sinomenine alleviates dorsal root ganglia inflammation to inhibit neuropathic pain via the p38 MAPK/CREB signalling pathway

An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat

Sun Ho Kim, Jin Mo Chung · Pain · 1992 · 3K citations

Pain Disorders, Peripheral Nerve Injury, Pain Medicine +27

Cytokine Mechanisms of Central Sensitization: Distinct and Overlapping Role of Interleukin-1β, Interleukin-6, and Tumor Necrosis Factor-α in Regulating Synaptic and Neuronal Activity in the Superficial Spinal Cord

Yasuhiko Kawasaki, Ling Zhang, Jen‐Kun Cheng et al. · Journal of Neuroscience · 2008 · 1.1K citations · Full text

Analgesia Mediated by a Direct Spinal Action of Narcotics

Tony L. Yaksh, Thomas A. Rudy · Science · 1976 · 944 citations

Potent Analgesia, Narcotic Analgetics, Pain Medicine +20

Tumor Necrosis Factor-α Induces Mechanical Allodynia after Spinal Nerve Ligation by Activation of p38 MAPK in Primary Sensory Neurons

Maria Schäfers, Camilla I. Svensson, Claudia Sommer et al. · Journal of Neuroscience · 2003 · 520 citations · Full text

Pain Disorders, Peripheral Nerve Injury, Pain Medicine +24

Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine

Zhi-Ye Zhuang, Yasuhiko Kawasaki, Ping-Heng Tan et al. · Brain Behavior and Immunity · 2006 · 357 citations · Full text

Inflammation, Pain Research, Spinal Cord Injury +12