Plasma <scp>d</scp>-glutamate levels for detecting mild cognitive impairment and Alzheimer’s disease: Machine learning approaches

Abstract

Peripheral plasma d-glutamate levels were associated with cognitive impairment and may therefore be a suitable peripheral biomarker for detecting MCI and AD. Rapid and cost-effective HPLC for biomarkers and machine learning algorithms may assist physicians in diagnosing MCI and AD in outpatient clinics.