A Novel Soluble ACE2 Variant with Prolonged Duration of Action Neutralizes SARS-CoV-2 Infection in Human Kidney Organoids - Concepedia

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Publication | Open Access

A Novel Soluble ACE2 Variant with Prolonged Duration of Action Neutralizes SARS-CoV-2 Infection in Human Kidney Organoids

DOI Full Paper Access

95

Citations

38

References

2021

Year

Jan Wysocki, Minghao Ye, Luise Hassler, Ashwani Gupta, Yuguo Wang, Vlad Nicoleascu, Glenn Randall, Jason A. Wertheim, Daniel Batlle

Journal of the American Society of Nephrology

Abstract

This novel ACE2 1-618-ABD can neutralize SARS-CoV-2 infectivity in human kidney organoids, and its prolonged duration of action should ensure improved efficacy to prevent viral escape and dosing convenience.

References

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