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Publication | Open Access

Clinical Responsiveness to All-trans Retinoic Acid Is Potentiated by LSD1 Inhibition and Associated with a Quiescent Transcriptome in Myeloid Malignancies

DOIFull Paper Access

46

Citations

41

References

2021

Year

Mina M. Tayari, Helena G. Dos Santos, Deukwoo Kwon, Terrence Bradley, Amber Thomassen, Charles Y. Chen, Yvonne Dinh, Aymee Perez, Arthur Zelent, Lluís Morey,
Clinical Cancer Research

Abstract

These data indicate that LSD1 inhibition sensitizes AML cells to ATRA and may restore ATRA responsiveness in subsets of patients with MDS and AML.

References

YearCitations

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