Two-pore channels affect EGF receptor signaling by receptor trafficking and expression

Control of EGF Receptor Signaling by Clathrin-Mediated Endocytosis

Amandio Vieira, Christophe Lamaze, Sandra L. Schmid · Science · 1996 · 999 citations

Signal Transduction, Egf Receptor Signaling, Tumor Microenvironment +14

NAADP mobilizes calcium from acidic organelles through two-pore channels

Peter Calcraft, Margarida Ruas, Zui Pan et al. · Nature · 2009 · 740 citations · Full text

Molecular Physiology, Signal Transduction, Medicine +7

Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation

Sara Sigismund, Elisabetta Argenzio, Daniela Tosoni et al. · Developmental Cell · 2008 · 665 citations · Full text

Signal Transduction, Signaling Pathway, Medicine +10

Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment

Yasuteru Sakurai, Andrey A. Kolokoltsov, Cheng‐Chang Chen et al. · Science · 2015 · 542 citations

Disease Treatment, Viral Pathogenesis, Immunology +17

Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization

Yibing Shan, Michael P. Eastwood, Xuewu Zhang et al. · Cell · 2012 · 363 citations · Full text

Signal Transduction, Signaling Pathway, Somatic Variant +9