The anti-inflammatory and analgesic effects of intraperitoneal melatonin after spinal nerve ligation are mediated by inhibition of the NF-κB/NLRP3 inflammasome signaling pathway

Quantitative assessment of tactile allodynia in the rat paw

Sandra R. Chaplan, Flemming W. Bach, J W Pogrel et al. · Journal of Neuroscience Methods · 1994 · 7.9K citations

Life Sciences, Neurobiology, Neuroscience +12

An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat

Sun Ho Kim, Jin Mo Chung · Pain · 1992 · 3K citations

Medicine, Neurology, Neuroscience +17

Melatonin alleviates inflammasome‐induced pyroptosis through inhibiting <scp>NF</scp>‐κB/<scp>GSDMD</scp> signal in mice adipose tissue

Zhenjiang Liu, Lu Gan, Yatao Xu et al. · Journal of Pineal Research · 2017 · 371 citations

Life Sciences, Immunology, Pharmacology +16

RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway

Xiaqiong Wang, Wei Jiang, Yiqing Yan et al. · Nature Immunology · 2014 · 323 citations · Full text

Life Sciences, Immunology, Molecular Biology +16

Spinal NF‐kB activation induces COX‐2 upregulation and contributes to inflammatory pain hypersensitivity

Kyung‐min Lee, Bong‐Seok Kang, Sun‐Joo Son et al. · European Journal of Neuroscience · 2004 · 253 citations · Full text

Nursing, Pharmacology, Inflammation +16