Electroacupuncture Regulates Inguinal White Adipose Tissue Browning by Promoting Sirtuin-1-Dependent PPARγ Deacetylation and Mitochondrial Biogenesis

Abstract

In conclusion, EA can remodel WAT to BAT through inducing SIRT-1 dependent PPAR<i>γ</i> deacetylation, and regulating PGC-1<i>α</i>-TFAM-UCP1 pathway to induce mitochondrial biogenesis. This may be one of the mechanisms by which EA affects weight loss.