Concepedia

Differential microRNA Expression in USP8-Mutated and Wild-Type Corticotroph Pituitary Tumors Reflect the Difference in Protein Ubiquitination Processes

Mateusz Bujko, Paulina Kober, Joanna Boresowicz, Natalia Rusetska, Natalia Żeber‐Lubecka, Agnieszka Paziewska, Monika Pękul, Grzegorz Zieliński, Andrzej Styk, Jacek Kunicki,

Journal of Clinical Medicine · 2021 · 19 citations · 27 references

DOIFull text

Open access

Abstract

Differences in microRNA expression in corticotropinomas stratified according to <i>USP8</i> status reflect disturbed ubiquitination processes, but do not correspond to differences in gene expression between these tumors.

References

27

Pituitary Adenomas with Invasion of the Cavernous Sinus Space

Engelbert Knosp, Erich Steiner, K. Kitz et al. · Neurosurgery · 1993 · 1.2K citations

, , +11

Mutations in the deubiquitinase gene USP8 cause Cushing's disease

Martín Reincke, Silviu Sbiera, Akira Hayakawa et al. · Nature Genetics · 2014 · 573 citations

, , +4

mirDIP 4.1—integrative database of human microRNA target predictions

Tomáš Tokár, Chiara Pastrello, Andrea E.M. Rossos et al. · Nucleic Acids Research · 2017 · 568 citations · Full text

Recurrent gain-of-function USP8 mutations in Cushing's disease

Zengyi Ma, Zhijian Song, Jianhua Chen et al. · Cell Research · 2015 · 346 citations · Full text

Pangenomic Classification of Pituitary Neuroendocrine Tumors

Mario Néou, Chiara Villa, Roberta Armignacco et al. · Cancer Cell · 2019 · 305 citations · Full text

, , +6