Detrimental effects of adolescent escalating low‐dose Δ⁹‐tetrahydrocannabinol leads to a specific bio‐behavioural profile in adult male rats

Abstract

Our adolescent low-dose THC animal model does not induce tangible psychotic-like effects, such as those reported in high-dose THC studies, but it impairs cognitive functions and points to hippocampal vulnerability and disrupted neurogenesis.