<scp>ACE2</scp> expression is elevated in airway epithelial cells from older and male healthy individuals but reduced in asthma

Abstract

Increased ACE2 expression occurs in older people and males. Asthma patients have reduced expression. Altered ACE2 expression in the lower airway may be an important factor in virus tropism and may in part explain susceptibility factors and why asthma patients are not over-represented in those with COVID-19 complications.