Tapentadol for the Treatment of Moderate-to-Severe Acute Pain in Children Under the Age of Two Years

Abstract

Tapentadol showed a favorable PK and safety profile in children <2 years of age. Multiple tapentadol OS dosing is efficacious and generally well tolerated in children ≥2 years and might also be a useful treatment option for children <2 years in need of strong analgesics.