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Computational and Synthetic approach with Biological Evaluation of Substituted Quinoline derivatives as small molecule L858R/T790M/C797S triple mutant EGFR inhibitors targeting resistance in Non-Small Cell Lung Cancer (NSCLC)

Medicinal ChemistryDrug TargetingMedicineNatural SciencesSmall MoleculesSubstituted QuinolineRational Drug DesignSynthetic ApproachBiological EvaluationAnti-cancer AgentDrug DevelopmentPharmacologyRadiation OncologyPharmaceutical ChemistryLung CancerTumor BiologyDrug Discovery