Concepedia

Polyprodrug with glutathione depletion and cascade drug activation for multi-drug resistance reversal

Xuan Xiao, Kewei Wang, Qingyu Zong, Yalan Tu, Yansong Dong, Youyong Yuan

Biomaterials · 2021 · 68 citations · 17 references

DOI

Concepts

References

17

Simultaneous Fenton‐like Ion Delivery and Glutathione Depletion by MnO<sub>2</sub>‐Based Nanoagent to Enhance Chemodynamic Therapy

Lisen Lin, Jibin Song, Liang Song et al. · Angewandte Chemie International Edition · 2018 · 1.5K citations

, , +17

Doxorubicin-Tethered Responsive Gold Nanoparticles Facilitate Intracellular Drug Delivery for Overcoming Multidrug Resistance in Cancer Cells

Feng Wang, Yucai Wang, Shuang Dou et al. · ACS Nano · 2011 · 807 citations

, , +16

Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes <i>p53</i> -deficient cancers to mTOR inhibition

Na Kong, Wei Tao, Xiang Ling et al. · Science Translational Medicine · 2019 · 306 citations · Full text

, , +17

Glutathione-Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy

Xiang Ling, Jiasheng Tu, Junqing Wang et al. · ACS Nano · 2018 · 262 citations

, , +17

Glutathione-Scavenging Poly(disulfide amide) Nanoparticles for the Effective Delivery of Pt(IV) Prodrugs and Reversal of Cisplatin Resistance

Xiang Ling, Xing Chen, Imogen A. Riddell et al. · Nano Letters · 2018 · 214 citations · Full text

, , +17