A novel humanized Frizzled-7-targeting antibody enhances antitumor effects of Bevacizumab against triple-negative breast cancer via blocking Wnt/β-catenin signaling pathway - Concepedia

Concepedia

Publication | Open Access

A novel humanized Frizzled-7-targeting antibody enhances antitumor effects of Bevacizumab against triple-negative breast cancer via blocking Wnt/β-catenin signaling pathway

DOI Full Paper Access

39

Citations

29

References

2021

Year

Wei Xie, Huijie Zhao, Fengxian Wang, Yiyun Wang, Yuan He, Tong Wang, Kunchi Zhang, Hao Yang, Zhaoli Zhou, Haibin Shi,

Journal of Experimental & Clinical Cancer Research

Abstract

SHH002-hu1 significantly enhances the anti-TNBC capacity of Bevacizumab, and shows the potential of preventing TNBC recurrence, suggesting SHH002-hu1 a good candidate for the synergistic therapy together with Bevacizumab.

References

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