Concepedia

Adiponectin receptor 1 variants contribute to hypertrophic cardiomyopathy that can be reversed by rapamycin

Perundurai S. Dhandapany, Soojeong Kang, Deepak Kashyap, Raksha Rajagopal, Nagalingam R. Sundaresan, Rajvir Singh, Kumarasamy Thangaraj, Shilpa Jayaprakash, Cholenahally Nanjappa Manjunath, Jayaprakash Shenthar,

Science Advances · 2021 · 28 citations · 33 references

DOIFull text

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Concepts

Abstract

Gene variants in adiponectin receptor 1 cause pathological enlarged hearts.

References

33

THE GLUCOSE FATTY-ACID CYCLE ITS ROLE IN INSULIN SENSITIVITY AND THE METABOLIC DISTURBANCES OF DIABETES MELLITUS

P J Randle, P. B. Garland, C. N. Hales et al. · The Lancet · 1963 · 5.2K citations

, , +10

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

Toshimasa Yamauchi, Junji Kamon, Yasuhiko Minokoshi et al. · Nature Medicine · 2002 · 4.2K citations

, , +16

Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

Toshimasa Yamauchi, Yasunori Nio, Toshiyuki Maki et al. · Nature Medicine · 2007 · 1.4K citations

, , +14

Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2–dependent mechanisms

Rei Shibata, Kaori Sato, David R. Pimentel et al. · Nature Medicine · 2005 · 977 citations · Full text

, , +13

Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1

Masato Iwabu, Toshimasa Yamauchi, Miki Okada‐Iwabu et al. · Nature · 2010 · 961 citations

, , +10