Targeting CDK7 suppresses super enhancer-linked inflammatory genes and alleviates CAR T cell-induced cytokine release syndrome - Concepedia

Concepedia

Publication | Open Access

Targeting CDK7 suppresses super enhancer-linked inflammatory genes and alleviates CAR T cell-induced cytokine release syndrome

DOI Full Paper Access

26

Citations

32

References

2021

Year

Wei Ye, Chong Li, Huifang Bian, Kairui Jin, Tingting Xu, Xiaomao Guo, Xueguan Lu, Fengtao Su

Molecular Cancer

Abstract

Our work indicates the CDK7-dependent transcription addiction of inflammatory genes. Targeting CDK7 is a promising strategy for treating CRS by inhibiting multiple cytokines.

References

	Year	Citations

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