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Plasma 3-hydroxyisobutyrate (3-HIB) and methylmalonic acid (MMA) are markers of hepatic mitochondrial fatty acid oxidation in male Wistar rats

DOIFull Paper Access

19

Citations

50

References

2021

Year

Mona Synnøve Bjune, Carine Lindquist, Marit Hallvardsdotter Stafsnes, Bodil Bjørndal, Per Bruheim, Thomas A. Aloysius, Ottar Nygård, Jon Skorve, Lise Madsen, Simon N. Dankel,
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Abstract

Our study provides new insight into TCA cycle-related metabolic changes associated with altered hepatic fatty acid flux, and identifies 3-HIB and MMA as novel circulating markers reflective of mitochondrial β-oxidation in male Wistar rats.

References

YearCitations

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