H3K27me3 loss indicates an increased risk of recurrence in the Tübingen meningioma cohort

Abstract

Loss of H3K27me3 combined with MIB1 labeling index are independent prognostic factors in meningioma. These data from the Tübingen meningioma cohort support the clinical utility of H3K27me3 immunohistochemical staining in meningioma and its integration into the routine histopathological workup.