A new antidiabetic and anti-inflammatory biflavonoid from <i>Schinus polygama</i> (Cav.) Cabrera leaves

Abstract

A new biflavonoid, luteolin-(6→8'')-apigenin was isolated from 80% methanol extract of <i>Schinus polygama</i> (Cav.) Cabrera leaves (Anacardiaceae). The structure was elucidated by 1D and 2D-NMR spectroscopic data. This compound exhibited <i>in vitro</i> antidiabetic effect via <i>α</i>-amylase assay. Furthermore, it possesses anti-inflammatory activity through membrane stabilization effect on erythrocytes.